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cholesterol inhibitors
(compound)
Summary
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Genetic Markers
Most Correlated Genes
Acot1
PDK4
HMGCR
ACOT2
EHHADH
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Pathway Enrichment
Most Correlated Biogroups
organic cyclic compound metabolic process
response to organic substance
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP
PILON_KLF1_TARGETS_DN
cytosol
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Curated Studies
Most Correlated Studies
Cardiac gene expression regulated by single fatty acids in wildtype and PPARa null mice
Testes expression profiles from ABDG8 KO and WT mice and ezetimibe treated ABDG8 KO mice
Peripheral atherosclerosis plaques after simvastatin, losartan or pioglitazone treatment
Hepatocytes treated with non-genotoxic carcinogens
HepG2 cells treated with genotoxic and non-genotoxic agents
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Literature
Most Relevant Literature
The Cholesterol Transport Inhibitor U18666A Interferes with Pseudorabies Virus Infection.
Discovery, synthesis and evaluation of novel cholesterol absorption inhibitors.
Pharmacokinetic Study of Oral 14C-Radiolabeled Hyzetimibe, A New Cholesterol Absorption Inhibitor.
Identification of Inhibitors of Cholesterol Transport Proteins Through the Synthesis of a Diverse, S…
Cholesterol-Lowering Effects of Asperidine B, a Pyrrolidine Derivative from the Soil-Derived Fungus …
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Clinical Trials
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Plaque REgression With Cholesterol Absorption Inhibitor or Synthesis Inhibitor Evaluated by IntraVas…
KF2019#1-trial: Effects of a Thrombocyte Inhibitor on a Cholesterol-lowering Drug
Evaluation of Patients Treated With HMG-CoA Reductase Inhibitors to Reach Cholesterol Target Values
Treatment With Rosuvastatin Versus Switching PI (Protease Inhibitor) in Patients HIV With High Chole…
Effect of an Inhibitor of Cholesterol Absorption on Vitamin D Levels
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