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QuickView for cholesterol transport (biogroup)


Body Atlas

Most Correlated Tissues

  1. Liver
  2. Fetal liver
  3. Adrenal gland cortex
  4. Myometrium
  5. Lung
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Disease Atlas

Most Correlated Diseases

  1. Alpha-1-antitrypsin deficiency
  2. Disorder of digestive system
  3. Liver cancer
  4. Disorder of lung
  5. Multiple organ failure
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Pharmaco Atlas

Most Correlated Compounds

  1. CGP 60474
  2. ARQ 197
  3. N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine
  4. BMS 777607
  5. PHA 767491
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. INSM2
  2. ANKRD2
  3. MUTYH
  4. HMOX2
  5. CHMP2A
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Melanoma A375 cells with CRISPR-targeted gene knockouts
  2. Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) expression profiles
  3. L1000 CMAP - Motor neuron MNEU.E cells treated with small molecule perturbagens
  4. L1000 CMAP - Colorectal cancer HT29.311 cells with CRISPR-targeted gene knockouts
  5. L1000 CMAP - Embryonic stem HUES3 cells treated with small molecule perturbagens
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Literature

Most Relevant Literature

  1. Aster-B coordinates with Arf1 to regulate mitochondrial cholesterol transport.
  2. Materno-fetal cholesterol transport during pregnancy.
  3. A new system to evaluate characteristics of Niemann-Pick C1 Like 1-mediated cholesterol transport us…
  4. Novel Mechanism of Cholesterol Transport by ABCA5 in Macrophages and Its Role in Dyslipidemia.
  5. Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins.
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Clinical Trials

Most Relevant Clinical Trials

  1. Alirocumab and Reverse Cholesterol Transport
  2. Modeling DNA Diversity in Reverse Cholesterol Transport
  3. The Effects of Dapagliflozin on HDL Particles Subtypes and Reverse Cholesterol Transport in Type 2 D…
  4. Impact of HIV and Its Treatment on Reverse Cholesterol Transport
  5. Mendelian Reverse Cholesterol Transport Study
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