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QuickView for claudin 18 (gene)


Body Atlas

Most Correlated Tissues

  1. Stomach pyloric
  2. Stomach cardiac
  3. Stomach
  4. Stomach fundus
  5. Lung
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Disease Atlas

Most Correlated Diseases

  1. Lung cancer
  2. Barrett's esophagus
  3. Esophagitis
  4. Disorder of mucous membrane
  5. Enteritis of small intestine
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Pharmaco Atlas

Most Correlated Compounds

  1. 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone
  2. 2-nitrofluorene
  3. Phenobarbital Sodium
  4. Diclofenac Sodium
  5. Mannitol
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. C15orf65
  2. CLDN18
  3. S100A6
  4. CIITA
  5. CASP10
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. Expression of the membrane tetraspanin claudin 18 on cancer cells promotes T lymphocyte infiltration…
  2. Nuclear factor E2-related factor 2 attenuates endotoxin-induced acute lung injury by up-regulating c…
  3. Claudin-18 Loss Alters Transcellular Chloride Flux but not Tight Junction Ion Selectivity in Gastric…
  4. SPAK-p38 MAPK signal pathway modulates claudin-18 and barrier function of alveolar epithelium after …
  5. FAP-targeted CAR-T suppresses MDSCs recruitment to improve the antitumor efficacy of claudin18.2-tar…
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Clinical Trials

Most Relevant Clinical Trials

  1. Claudin 18.2-Targeted Chimeric Antigen Receptor T-cells in Subjects With Unresectable, Locally Advan…
  2. TAC T-cells for the Treatment of Claudin 18.2 Positive Solid Tumors (TACTIC-3)
  3. Study of SYSA1801 in the Treatment of Claudin( CLDN) 18.2 Positive Advanced Malignant Solid Tumor
  4. Dose Escalation and Expansion Study of CPO102, an Anti-claudin 18.2 ADC in Patients With Advanced Ca…
  5. A Study to Assess the Efficacy and Safety of IMAB362 in Combination With Nab-Paclitaxel and Gemcitab…
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