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(e.g. rs2300478, SNCA, glucose metabolic process, Influenza, Adipose tissue, Clofibrate)
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QuickView for complement 5a receptor (compound)


Genetic Markers

Most Correlated Genes

  1. No genes found
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Pathway Enrichment

Most Correlated Biogroups

  1. No biogroups found
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
  2. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
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Literature

Most Relevant Literature

  1. The role of C5a receptors in autoimmunity.
  2. Anaphylatoxin C5a receptor signaling induces mitochondrial fusion and sensitizes retinal pigment epi…
  3. Loss of C3a and C5a receptors promotes adipocyte browning and attenuates diet-induced obesity via ac…
  4. Blockade of C5a receptor unleashes tumor-associated macrophage antitumor response and enhances CXCL9…
  5. Pharmacological and clinical profiles of avacopan (TAVNEOS® capsule), a selective C5a receptor antag…
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Clinical Trials

Most Relevant Clinical Trials

  1. Complement C5a Receptors in Hidradenitis Suppurativa
  2. Complement Inhibition in aHUS Dialysis Patients
  3. A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of CCX168 in Healthy Participants
  4. A Phase 3 Clinical Trial of CCX168 (Avacopan) in Patients With ANCA-Associated Vasculitis
  5. Clinical Trial to Evaluate Safety and Efficacy of CCX168 in ANCA-Associated Vasculitis
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