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complement C3b
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Genetic Markers
Most Correlated Genes
PLPP3
INHBA
SLAMF7
TNFSF15
HES1
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Pathway Enrichment
Most Correlated Biogroups
PILON_KLF1_TARGETS_DN
GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_UP
GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_UP
GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN
GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_DN
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Curated Studies
Most Correlated Studies
Polymorphonuclear leukocytes (PMNs) and PBMCs of Job's patients incubated with IgG and C3bi beads
L1000 CMAP - Prostate carcinoma VCaP cells treated with ligand perturbagens
L1000 CMAP - Adenocarcinoma of breast MCF7 cells treated with ligand perturbagens
L1000 CMAP - Amelanotic malignant melanoma of skin A375 cells treated with ligand perturbagens
L1000 CMAP - Colorectal cancer HT29 cells treated with ligand perturbagens
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Literature
Most Relevant Literature
A bifunctional amylopullulanase of Streptococcus suis ApuA contributes to immune evasion by interact…
Purified complement C3b triggers phagocytosis and activation of human neutrophils via complement rec…
HylS', a fragment of truncated hyaluronidase of Streptococcus suis, contributes to immune evasion by…
Trypanosoma brucei Invariant Surface gp65 Inhibits the Alternative Pathway of Complement by Accelera…
Recruiting the Immune System against Pathogenic Bacteria Using High-Affinity Chimeric Tags.
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Clinical Trials
Most Relevant Clinical Trials
First-In-Human Clinical Study of the C3 Complement Inhibitor AMY- 101 in Healthy Male Volunteers
Study of Efficacy and Safety of NM8074 in Adult PNH Patients Who Are Naive to Complement Inhibitor T…
Complement Inhibition: Attacking the Overshooting Inflammation @Fter Traumatic Brain Injury
Erythrocyte Complement Receptor 1 and Alzheimer Disease
Study of NM8074 in Adult PNH Patients With Inadequate Response to Soliris
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