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depurination
(biogroup)
Summary
General Info
Body Atlas
Most Correlated Tissues
Tonsil
Prefrontal cortex
Testes
Lymph nodes
Parotid gland
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Disease Atlas
Most Correlated Diseases
Legionella infection
Sepsis due to Streptococcus agalactiae
Bacterial sepsis of newborn
Systemic infection
Disorder of uterus
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Pharmaco Atlas
Most Correlated Compounds
geldanamycin
AZD1480
CC 401
((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide)
MLN-0128
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Knockdown Atlas
Most Correlated Gene Perturbations
ISX
DIDO1
POLB
CYP2C19
LAT
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Curated Studies
Most Correlated Studies
Breast cancer cerebral xenografts treated with carboplatin and ABT888
L1000 CMAP - Adipose MSC ASC52telo cells with shRNA-mediated gene knockdown
L1000 CMAP - Hepatocellular carcinoma Hep G2 cells with shRNA-mediated gene knockdown (1 of 2)
L1000 CMAP Breast cancer MCF7 cells with gene overexpression perturbations
L1000 CMAP - Breast carcinoma BT20 cells treated with small molecule perturbagens
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Literature
Most Relevant Literature
Polyvinyl pyrrolidone promotes DNA cleavage by a ROS-independent and depurination mechanism.
The P1/P2 proteins of the human ribosomal stalk are required for ribosome binding and depurination b…
Shiga toxin 1 is more dependent on the P proteins of the ribosomal stalk for depurination activity t…
Label-free fluorescence detection of the depurination activity of ribosome inactivating protein toxi…
A relatively low level of ribosome depurination by mutant forms of ricin toxin A chain can trigger p…
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Clinical Trials
Most Relevant Clinical Trials
Study of Urine Samples From Women With Newly Diagnosed Breast Cancer Enrolled on Clinical Trial UNMC…
Effect of Tamoxifen or an Aromatase Inhibitor on Estrogen Metabolism in Women Undergoing Treatment f…
Studying Biomarkers in Nipple Fluid, Urine, and Blood Samples From Women With Newly Diagnosed Ductal…
Chemopreventive Action of Mesalazine on Colorectal Cancer: a Pilot Study for an "in Vivo" Evaluation…
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