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direct thrombin inhibitor
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Summary
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Genetic Markers
Most Correlated Genes
F2
PCOLCE
STAC3
KNG1
GCK
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Pathway Enrichment
Most Correlated Biogroups
protein activation cascade
HALLMARK_COMPLEMENT
HALLMARK_ALLOGRAFT_REJECTION
GSE41978_ID2_KO_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP
GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_DC_DN
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Curated Studies
Most Correlated Studies
Drug target sets for approved compounds
L1000 CMAP - Colorectal cancer HT29 cells treated with ligand perturbagens
L1000 CMAP - Prostate carcinoma VCaP cells treated with ligand perturbagens
L1000 CMAP - Lung cancer A549 cells treated with ligand perturbagens
L1000 CMAP - Adenocarcinoma of breast MCF7 cells treated with ligand perturbagens
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Literature
Most Relevant Literature
Antithrombin Deficiency: Frequency in Patients with Thrombosis and Thrombophilic Families.
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Preoperative Antithrombin Suppl…
Correlation of Antithrombin Functional Status and Levels with Liver Fibrosis in Patients with Hepati…
Anticoagulant Use During Extracorporeal Membrane Oxygenation Using Heparin and Direct Thrombin Inhib…
Direct thrombin inhibitors as alternatives to heparin to preserve lung growth and function in a muri…
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Clinical Trials
Most Relevant Clinical Trials
Direct Thrombin Inhibitors Versus LMWH in Staphylococcus Aureus Bacteraemia
Twice-daily Oral Direct Thrombin Inhibitor Dabigatran Etexilate in the Long Term Prevention of Recur…
Thrombin Regulated Platelet Activation
Influence of Vorapaxar on Thrombin Generation and Coagulability
Apixaban + DAPT in Lowering Platelet Reactivity and Thrombin Generation
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