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farnesyltransferase
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Curated Studies
Most Correlated Studies
Fibroblasts overexpressing prelamin A/progerin + treated with farnesyltransferase inibitor L-744832
Bone marrow from AML patients responsive or non-responsive to tipifarnib
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Literature
Most Relevant Literature
Expression of farnesyltransferase in primary liver cancer.
Molecular dynamics analysis of a series of 22 potential farnesyltransferase substrates containing a …
Peptidomimetic modification improves cell permeation of bivalent farnesyltransferase inhibitors.
Insights into the mechanistic dichotomy of the protein farnesyltransferase peptide substrates CVIM a…
Characterization of the GGPP synthase gene family in Arabidopsis thaliana.
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Clinical Trials
Most Relevant Clinical Trials
Phase II Trial of Lonafarnib (a Farnesyltransferase Inhibitor) for Progeria
Phase II Study of SCH66336, A Farnesyltransferase Inhibitor in Chronic Myelogenous Leukemia (CML)
A Phase II Study Of The Farnesyltransferase Inhibitor ZANESTRA (R115777, NSC #702818, IND #58,359) I…
BMS-214662 in Treating Patients With Advanced Solid Tumors
Tipifarnib and Gemcitabine Hydrochloride in Treating Women With Metastatic Breast Cancer
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