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QuickView for flavopiridol (compound)


Genetic Markers

Most Correlated Genes

  1. XIST
  2. RBP4
  3. CRIP1
  4. TNFAIP3
  5. ID4
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Pathway Enrichment

Most Correlated Biogroups

  1. regulation of nitrogen compound metabolic process
  2. cell periphery
  3. organic cyclic compound binding
  4. heterocyclic compound binding
  5. vesicle
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Curated Studies

Most Correlated Studies

  1. A2780 and MCF7 cancer cell lines treated with CDK, HSP90, and topoisomerase inhibitors
  2. L1000 CMAP - Breast adenocarcinoma SKBR3 cells treated with small molecule perturbagens
  3. L1000 CMAP - Breast carcinoma BT20 cells treated with small molecule perturbagens
  4. L1000 CMAP - Prostate cancer LNCAP cells treated with small molecule perturbagens
  5. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
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Literature

Most Relevant Literature

  1. The Pharmacological Implications of Flavopiridol: An Updated Overview.
  2. Analytical Quality-by-Design-Based Systematic Optimization of RP-HPLC Method Conditions to Analyze S…
  3. Enhanced Anti-tumor Effect of Flavopiridol in Combination With Gemcitabine in Pancreatic Cancer.
  4. Flavopiridol Protects against Fungal Keratitis due to Aspergillus fumigatus by Alleviating Inflammat…
  5. Modulation of Primary Cilia by Alvocidib Inhibition of CILK1.
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Clinical Trials

Most Relevant Clinical Trials

  1. Flavopiridol in Treating Patients With Chronic Lymphocytic Leukemia
  2. Flavopiridol, Cytarabine, and Mitoxantrone in Treating Patients With Acute Leukemia
  3. Gemcitabine Plus Flavopiridol in Treating Patients With Advanced Solid Tumors
  4. Flavopiridol to Treat Relapsed Mantle Cell Lymphoma or Diffuse Large B-Cell Lymphoma
  5. Flavopiridol in Treating Patients With Recurrent Prostate Cancer
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