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fostamatinib
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
XIST
RBP4
CRIP1
LCN2
COL11A1
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Pathway Enrichment
Most Correlated Biogroups
regulation of nitrogen compound metabolic process
organic cyclic compound binding
cytosol
heterocyclic compound binding
organic cyclic compound metabolic process
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Curated Studies
Most Correlated Studies
Liver cancer Huh7 cells sorafenib resistant treated with fostamatinib
L1000 CMAP - Breast adenocarcinoma SKBR3 cells treated with small molecule perturbagens
L1000 CMAP - Breast carcinoma BT20 cells treated with small molecule perturbagens
L1000 CMAP - Prostate cancer LNCAP cells treated with small molecule perturbagens
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
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Literature
Most Relevant Literature
A proof-of-concept open-label clinical trial of spleen tyrosine kinase antagonism using fostamatinib…
Addressing thrombosis concerns in immune thrombocytopenia: the role of fostamatinib in immune thromb…
Fostamatinib for the treatment of Japanese patients with primary immune thrombocytopenia: A phase 3,…
Signaling network analysis reveals fostamatinib as a potential drug to control platelet hyperactivat…
Fostamatinib for the treatment of warm antibody autoimmune hemolytic anemia: Phase 2, multicenter, o…
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Clinical Trials
Most Relevant Clinical Trials
Effects of Administration of Fostamatinib on Blood Concentrations of Rifampicin in Healthy Subjects.
Fostamatinib for Hospitalized Adults With COVID-19
Clinical Trial of Combined Fostamatinib and Paclitaxel in Ovarian Cancer
A Single and Multiple Dose Study to Assess Blood and Urine Drug Levels of Fostamatinib in Healthy Ja…
Extension Study (Extended Access) of Syk-inhibition Using Fostamatinib to Treat Posttransplant Immun…
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