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hypercholesterolaemia
(phenotype)
Summary
General Info
Genetic Markers
Most Correlated Genes
Most Correlated SNPs
APOB
LDLRAP1
CETP
PPARA
HLA-DRB4
No SNPs found
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Pathway Enrichment
Most Correlated Biogroups
GSE22886_CD4_TCELL_VS_BCELL_NAIVE_UP
lipid transport
REACTOME_LIPOPROTEIN_METABOLISM
sterol metabolic process
regulation of plasma lipoprotein particle levels
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Curated Studies
Most Correlated Studies
PBMC gene expression in ischemic stroke patients
Huh7 cell gene expression in response to HDL from normal and familial hypercholesterolemia patients
OMIM - Hypercholesterolemia
Monocytes from blood of healthy donors and hypercholestoremia patients before or after statins
Atherosclerotic markersin patients with familial hypercholesterolemia
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Literature
Most Relevant Literature
Pitavastatin: A Review in Hypercholesterolemia.
Lomitapide for the treatment of hypercholesterolemia.
Hypercholesterolemia impairs oxytocin-induced uterine contractility in late pregnant mouse.
Cutaneous manifestations in familial hypercholesterolaemia.
Recent advances in the management and implementation of care for familial hypercholesterolaemia.
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Clinical Trials
Most Relevant Clinical Trials
EAS Familial Hypercholesterolaemia Studies Collaboration
Genetic Causes of Hypercholesterolaemia in the Emirati Population
An Study to Evaluate Rosuvastatin in Children and Adolescents With Familial Hypercholesterolaemia
Greek Registry - Familial Hypercholesterolaemia
Centralized Pan-South African Survey on the Undertreatment of Hypercholesterolaemia
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