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immunoconjugate
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Summary
General Info
Genetic Markers
Most Correlated Genes
CD80
CD86
HIST1H3G
MYH2
HIST1H2AJ
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Pathway Enrichment
Most Correlated Biogroups
TTTNNANAGCYR_UNKNOWN
REACTOME_IMMUNE_SYSTEM
GAL_LEUKEMIC_STEM_CELL_DN
immune response
positive regulation of immune system process
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Curated Studies
Most Correlated Studies
Germinal B cells from spleen of systemic lupus erythematosus mice treated with CTLA4Ig & anti-CD40L
Whole blood of rheumatoid arthritis patients treated with abatacept
CD4-positive T cells and antigen presenting cells from OVA TCR mice treated with abatacept
T-cells expression after treatment with leukocyte costimulatory blockade antibodies
Drug target sets for approved compounds
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Literature
Most Relevant Literature
Designing immunoconjugates for cancer therapy.
Immunoconjugates and long circulating systems: origins, current state of the art and future directio…
Tailored immunoconjugate therapy depending on a quantity of tumor stroma.
Risks and untoward toxicities of antibody-based immunoconjugates.
Immunoconjugates against solid tumors: mind the gap.
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Clinical Trials
Most Relevant Clinical Trials
ItaliaN Observational Study of Patients With Acute Lymphoblastic Leukemia Treated With Anti-CD22 Imm…
A Phase I/II Open-Label, Non-Randomized Dose Escalation Study of Immunoconjugate L-DOS47
Safety/Efficacy Study of Immunoconjugate With Docetaxel in Non-small Cell Lung Carcinoma
Monoclonal Antibody Therapy in Treating Patients With Recurrent Acute Lymphoblastic Leukemia or Non-…
Expanded Access Request Program for Belantamab Mafodotin (GSK2857916) in Multiple Myeloma
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