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interleukin-5
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Summary
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Genetic Markers
Most Correlated Genes
FOSB
IGHM
FOS
CCL22
NR4A2
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Pathway Enrichment
Most Correlated Biogroups
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP
MARSON_BOUND_BY_E2F4_UNSTIMULATED
nucleoplasm
heterocyclic compound binding
organic cyclic compound binding
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Curated Studies
Most Correlated Studies
Differentiation of naïve B cells into memory B cells and plasma cells
Blasts, pre-plasma blasts, and B cells from Prdm1-GFP knockin null mice
Low-density bone marrow cells stimulated with interleukin-5 for 4d and 10d
Reconstituted epidermis cultures treated with IL-1 family cytokines
Peripheral blood basophils stimulated in vitro with various interleukins, anti-IgE, fMLP or NGF
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Literature
Most Relevant Literature
Targeting the interleukin-5 pathway in EGPA: evidence, uncertainties and opportunities.
Cardiovascular safety of genetically proxied interleukin-5 inhibition: A mendelian randomization stu…
Multicentric IL-5-positive Castleman Disease With Nephrotic Syndrome Relapsed After Rituximab Treatm…
A web server for predicting and scanning of IL-5 inducing peptides using alignment-free and alignmen…
Regulatory T-cells and IL-5 mediate pain outcomes in a preclinical model of chronic muscle pain.
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Clinical Trials
Most Relevant Clinical Trials
Pharmacodynamic Biomarkers to Support Biosimilar Development: Interleukin-5 Antagonists
Effects of Anti-IL5 Biological Treatments on Blood IgE Levels in Severe Asthmatic Patients
Impulse Oscillometry Measurements in Severe Eosinophilic Asthmatics Before and After Anti-IL-5 Facto…
Blood Leukocyte Profiling in Eosinophilic Type 2 Asthma: Influence of Systemic IL-5 Targeting
Nebulized Resveratrol Plus Carboxymethyl-β-Glucan for Reducing IL-5 in Children With Allergic Rhinit…
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