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isocitrate
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Curated Studies
Most Correlated Studies
CD45+ cells from IDH1 mutant AML-PDX mouse bone marrow treated with IDH1 mutant inhibitor BAY1436032
Glioma xenografts from BT142 and GB10 glioma cells-injected mice treated with IDH1 inhibitor MRK-A
Oligodendroglioma xenografts with IDH1 R132H mutation in mice treated with AGI-5198
Bone marrow CD45+ cells from AML-patient derived xenograft mice treated with BAY, AZA, or both
Erythroid progenitor CD71+ cells from umbilical cord blood treated with Enasidenib (AG221)
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Literature
Most Relevant Literature
Purification and characterization of NADP-isocitrate dehydrogenase from skeletal muscle of Urocitell…
Pharmacophore-based Identification of Potential Mutant Isocitrate Dehydrogenases I/2 Inhibitors: An …
Fluorometric determination of isocitrate dehydrogenase (EC 1.1.1.42; 1; NADP+ dependent) in ruminant…
Challenges for the development of mutant isocitrate dehydrogenases 1 inhibitors to treat glioma.
Molecular insights into the catalysis and regulation of mammalian NAD-dependent isocitrate dehydroge…
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Clinical Trials
Most Relevant Clinical Trials
An Efficacy and Safety Study of AG-221 (CC-90007) Versus Conventional Care Regimens in Older Subject…
Safety and Efficacy of L19TNF in Patients With Isocitrate Dehydrogenase (IDH) Wildtype WHO Grade III…
Using the Anticancer Drug Olaparib to Treat Relapsed/Refractory Acute Myeloid Leukemia or Myelodyspl…
A Study to Assess the Safety and Efficacy of Two Combinations of Isocitrate Dehydrogenase (IDH) Muta…
Phase 1/2 Study of Enasidenib (AG-221) in Adults With Advanced Hematologic Malignancies With an Isoc…
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