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leucovorin
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
TYMS
CHST3
CYP3A4
MYH13
PPP3R1
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Pathway Enrichment
Most Correlated Biogroups
SENESE_HDAC1_TARGETS_UP
SENESE_HDAC3_TARGETS_UP
small molecule binding
MODULE_12
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP
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Curated Studies
Most Correlated Studies
Colorectal cancer gene expression in responders and non-responders to FOLFOX therapy
Uterus tissue from Folr4 knockout mice treated with folinic acid
Prediction of response of colorectal patients to mFOLFOX6 and Bevacizumab
Colorectal cancer biopsies collected prospectively from therapy responders and non-responders
Metastatic colorectal tumors from responder and nonresponder patients undergoing the FOLFIRI regimen
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Literature
Most Relevant Literature
High vs. low-dose leucovorin in regimens with fluorouracil in colorectal cancer therapy.
A Randomized Phase III Study of Arfolitixorin versus Leucovorin with 5-Fluorouracil, Oxaliplatin, an…
Liposomal irinotecan plus fluorouracil/leucovorin in older patients with advanced pancreatic cancer:…
pH-sensitive nanoparticles containing 5-fluorouracil and leucovorin as an improved anti-cancer optio…
FLOT or CROSS for gastroesophageal junction cancers-is the debate over yet?
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Clinical Trials
Most Relevant Clinical Trials
Treatment of Social and Language Deficits With Leucovorin for Young Children With Autism
Phase II Study of Folotyn With Leucovorin to Prevent/Reduce Mucositis in Patients With Hematological…
Pyrimethamine, Sulfadiazine, and Leucovorin in Treating Patients With Congenital Toxoplasmosis
Leucovorin for the Treatment of 5 q Minus Syndrome
Open-label Leucovorin Pharmacokinetic Study in Patients Receiving High Dose Methotrexate With or Wit…
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