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QuickView for lumiracoxib (compound)


Genetic Markers

Most Correlated Genes

  1. MMD2
  2. Mup5
  3. GPR84
  4. INMT
  5. WNT6
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Pathway Enrichment

Most Correlated Biogroups

  1. CHEN_METABOLIC_SYNDROM_NETWORK
  2. MODULE_84
  3. MCLACHLAN_DENTAL_CARIES_UP
  4. PILON_KLF1_TARGETS_DN
  5. response to organic substance
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Curated Studies

Most Correlated Studies

  1. Liver tissues from rats after treatment with different compounds
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Literature

Most Relevant Literature

  1. A validated UHPLC-MS/MS method for simultaneous determination of lumiracoxib and its hydroxylation a…
  2. Bioactivation of lumiracoxib in human liver microsomes: Formation of GSH- and amino adducts through …
  3. The early inhibition of the COX-2 pathway in viperid phospholipase A2-induced skeletal muscle myotox…
  4. The pharmacokinetics and metabolism of lumiracoxib in chimeric humanized and murinized FRG mice.
  5. Exploring the molecular determinants of substrate-selective inhibition of cyclooxygenase-2 by lumira…
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Clinical Trials

Most Relevant Clinical Trials

  1. Efficacy and Safety of Lumiracoxib
  2. Safety and Efficacy of Lumiracoxib in Patients With Osteoarthritis and With Controlled Hypertension
  3. Efficacy and Safety of Lumiracoxib in Patients With Primary Knee Osteoarthritis(OA)
  4. Video Capsule Endoscopy to Investigate the Safety and Tolerability of Lumiracoxib in the Small Bowel
  5. Efficacy and Safety of Lumiracoxib in Patients With Primary Knee Osteoarthritis (OA)
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