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QuickView for mismatch repair (biogroup)


Body Atlas

Most Correlated Tissues

  1. Tonsil
  2. Duodenum
  3. Vena cava
  4. Hematopoietic stem cell of bone marrow
  5. Adrenal gland cortex
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Disease Atlas

Most Correlated Diseases

  1. Vesicular stomatitis Indiana virus disease
  2. Listeriosis
  3. Drug resistance
  4. Alpha-1-antitrypsin deficiency
  5. Poisoning by drug AND/OR medicinal substance
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Pharmaco Atlas

Most Correlated Compounds

  1. 5-(6)-carboxyfluorescein diacetate succinimidyl ester
  2. WYE 125132
  3. Amsacrine
  4. AZD8055
  5. 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. AURKB
  2. KDM5A
  3. NOP2
  4. GRHPR
  5. RPS6
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Neural progenitor NPC.CAS9 cells treated with small molecule perturbagens
  2. Cancer Gene Census - mutations in cancer genes
  3. The Immunological Genome Project - Immune cell lineage differentiation and maturation
  4. L1000 CMAP - Neural progenitor NPC cells treated with small molecule perturbagens
  5. L1000 CMAP - Non-small cell lung cancer A549.311 cells with CRISPR targeted gene knockouts
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Literature

Most Relevant Literature

  1. Immunosensitivity cuts across mismatch repair status in colorectal cancer.
  2. Mismatch repair enzymes regulate telomere recombination in Saccharomycescerevisiae.
  3. Combining single-molecule and structural studies reveals protein and DNA conformations and assemblie…
  4. Microsatellite instability and mismatch repair protein deficiency: equal predictive markers?
  5. Action-At-A-Distance in DNA Mismatch Repair: Mechanistic Insights and Models for How DNA and Repair …
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Clinical Trials

Most Relevant Clinical Trials

  1. Tislelizumab for the Treatment of Recurrent Mismatch Repair Deficient Endometrial Cancer
  2. Lynch Syndrome Can be Diagnosed Just From Somatic Mismatch Repair Mutation
  3. Pembrolizumab With Sitravatinib in Recurrent Endometrial Cancer and Other Solid Tumors With Deficien…
  4. Pembrolizumab Before Surgery for the Treatment of Mismatch Repair Deficient Locally Advanced Solid C…
  5. Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent En…
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