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p53 binds
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Curated Studies
Most Correlated Studies
Effect of stresses on p53 binding and transactivation landscape in human cancer cells
HCT116 (p53 null/wild type) and FL2 cell lines after DNA damage and/or DINO knockdown
Splenic B and non B cells with or without P53 knockout mice and irradiated with 7Gy IR
Profiling of life-extending conditions: dietary restriction, p53 knockdown or sir2 overexpression
U251 glioblastoma cells by binding of mutant p53 to intronic and intergenic sequences
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Literature
Most Relevant Literature
p53 binds the mdmx mRNA and controls its translation.
Tumor-suppressor p53 specifically binds to miR-29c-3p and reduces ADAM12 expression in hepatocellula…
Computational studies suggest compounds restoring function of p53 cancer mutants can bind SARS-CoV-2…
Two p53 tetramers bind one consensus DNA response element.
Wild-type p53 binds to MYC promoter G-quadruplex.
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Clinical Trials
Most Relevant Clinical Trials
CT-011 and p53 Genetic Vaccine for Advanced Solid Tumors
Phase II Study of Metastatic Cancer That Overexpresses P53 Using Lymphodepleting Conditioning Follow…
Arsenic Trioxide in Recurrent and Metastatic Ovarian Cancer and Endometrial Cancer With P53 Mutation
Arsenic Trioxide in Refractory Solid Tumors With Rescuable p53 Mutation
Sodium Stibogluconate in the MDS/AML With One of the 65 Defined p53 Mutations
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