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polylysine
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
IFIT1
CCL8
IFI44L
IFIT3
IFI27
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Pathway Enrichment
Most Correlated Biogroups
GSE13485_CTRL_VS_DAY7_YF17D_VACCINE_PBMC_DN
GSE42724_NAIVE_BCELL_VS_PLASMABLAST_UP
GSE13485_DAY3_VS_DAY7_YF17D_VACCINE_PBMC_DN
HALLMARK_INTERFERON_GAMMA_RESPONSE
GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_DN
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Curated Studies
Most Correlated Studies
Transplanted HCmel3 mouse melanomas relapsing post adoptive T-cell (ACT) therapy
Melanoma or endothelial cell lines stimulated with TLR agonists
Synthetic double stranded RNA (poly-ICLC) inducation of innate immunity
Drug target sets for approved compounds
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Literature
Most Relevant Literature
Preference toward a polylysine enantiomer in inhibiting prions.
Polylysine copolymers for gene delivery.
Comparative study on the in vitro cytotoxicity of linear, dendritic, and hyperbranched polylysine an…
In vitro transfection with plasmid DNA using polylysine copolymers.
In vitro transfection with oligonucleotide DNA using polylysine copolymers.
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Clinical Trials
Most Relevant Clinical Trials
Tear Film Break-up Time After Instillation of Artificial Tears
Poly-ICLC (Hiltonol) and Anti-PD1 or Anti-PD-L1
In Situ, Autologous Therapeutic Vaccination Against Solid Cancers With Intratumoral Hiltonol®
Safety and Efficacy Study of SL-701, a Glioma-Associated Antigen Vaccine To Treat Recurrent Glioblas…
Intratumoral Poly-ICLC Plus Low Dose Local Radiation in Low Grade Recurrent B and T Cell Lymphoma
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