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prelamin
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Curated Studies
Most Correlated Studies
Fibroblasts overexpressing prelamin A/progerin + treated with farnesyltransferase inibitor L-744832
Oral, breast and lung cancer cell lines depleted of ZMPSTE24
Mouse embryonic fibroblast gene expression in Zmpste24 knockout
Fibroblast expression changes in a Hutchinson-Gilford progeria syndrome patient
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Literature
Most Relevant Literature
Prelamin A and ZMPSTE24 in premature and physiological aging.
Effect of β-Estradiol on Adipogenesis in a 3T3-L1 Cell Model of Prelamin A Accumulation.
Abolishing the prelamin A ZMPSTE24 cleavage site leads to progeroid phenotypes with near-normal long…
Cell immortalization facilitates prelamin A clearance by increasing both cell proliferation and auto…
ZP3 and AIPL1 participate in GVBD of mouse oocytes by affecting the nuclear membrane localization an…
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Clinical Trials
Most Relevant Clinical Trials
Accelerated Aging, HIV Infection, Antiretroviral Therapies
Insulin Regulated Amino Peptidase in Patients With Familial Lipodystrophy of DUNNIGAN
Study of Zoledronic Acid, Pravastatin, and Lonafarnib for Patients With Progeria
Mandibular Reconstruction With Axially Vascularised Bone Substitutes
Treatment of the Hutchinson-Gilford Progeria Syndrome With a Combination of Pravastatin and Zoledron…
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