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QuickView for presenilins (compound)


Genetic Markers

Most Correlated Genes

  1. No genes found
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Pathway Enrichment

Most Correlated Biogroups

  1. No biogroups found
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Curated Studies

Most Correlated Studies

  1. Induced pluripotent stem cell models of Alzheimer's disease and mutant presenilin 2
  2. Presenilin homologous protease hIMP1-dependent gene expression in HEK-293 embryonic kidney cells
  3. Effect of Polytopic protease downregulation on mouse brain
  4. Cholinergic neurons from iPSCs expressing PSEN1 wildtype or PSEN1 P117L mutation
  5. Fibroblasts with a targeted knockdown of HPRT
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Literature

Most Relevant Literature

  1. Presenilin is involved in larval-pupal metamorphosis development of Bombyx mori.
  2. Structure and function of SPP/SPPL proteases: insights from biochemical evidence and predictive mode…
  3. Probing the Structure and Function Relationships of Presenilin by Substituted-Cysteine Accessibility…
  4. Beyond γ-secretase activity: The multifunctional nature of presenilins in cell signalling pathways.
  5. Presenilins and mitochondria-an intriguing link: mini-review.
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Clinical Trials

Most Relevant Clinical Trials

  1. Repurposing Bromocriptine for Abeta Metabolism in Alzheimer's Disease
  2. The Chinese Familial Alzheimer's Network
  3. Efficacy and Safety of Curcumin Formulation in Alzheimer's Disease
  4. Late Onset Alzheimer's Disease
  5. Apolipoprotein E Gene and Functional MRI
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