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(e.g. Arthritis, Neuron, Early pregnancy factor, Trichostatin A, rs2476601, PRKCA)
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QuickView for pro- opiomelanocortin (compound)


Genetic Markers

Most Correlated Genes

  1. PAK3
  2. MBP
  3. PROCR
  4. WFDC3
  5. HKDC1
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Pathway Enrichment

Most Correlated Biogroups

  1. cell periphery
  2. regulation of nitrogen compound metabolic process
  3. cell differentiation
  4. TGGAAA_NFAT_Q4_01
  5. vesicle
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Curated Studies

Most Correlated Studies

  1. Adrenocortical cell gene expression in fetal/adult cells treated with adrenocorticotropic hormone
  2. Microarray analysis of the effects of ASP/MSH in melan-a melanocytes
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Literature

Most Relevant Literature

  1. AgRP/NPY and POMC neurons in the arcuate nucleus and their potential role in treatment of obesity.
  2. Transgenerational inheritance of fetal alcohol effects on proopiomelanocortin gene expression and me…
  3. Inflammatory Milieu Induces Mitochondrial Alterations and Neuronal Activations in Hypothalamic POMC …
  4. Controlling hypothalamic DNA methylation at the Pomc promoter does not regulate weight gain during t…
  5. Increased intrinsic and synaptic excitability of hypothalamic POMC neurons underlies chronic stress-…
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Clinical Trials

Most Relevant Clinical Trials

  1. Setmelanotide for the Treatment of Early-Onset POMC Deficiency Obesity
  2. Phase 3 Crossover Trial of Two Formulations of Setmelanotide in Patients With Specific Gene Defects …
  3. Low Level Laser Treatment (LLLT) and Lorcaserin for Weight Management
  4. Preoperative Bexarotene Treatment for Cushing's Disease
  5. Adrenocorticotropic Hormone (ACTH) Effects on Myelination in Subjects With MS
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