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riluzole
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
GRIN3A
SCN5A
FGR
TWF1
RAD23B
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Pathway Enrichment
Most Correlated Biogroups
membrane depolarization during cardiac muscle cell action potential
Predicted Gene Targets for miR-421
MARSON_BOUND_BY_FOXP3_STIMULATED
GSE21360_PRIMARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN
JOHNSTONE_PARVB_TARGETS_3_DN
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Curated Studies
Most Correlated Studies
Cortical neurons exposed to excitotoxic NMDA and potentially neuroprotective compounds
Breast cancer MDA-MB-231 cells treated with glutamate receptor antagonist riluzole
Cerebrocortical cells treated with blood-brain barrier penetrant clinic-tested drugs
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
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Literature
Most Relevant Literature
Biochemical effects of riluzole on Leishmania parasites.
Riluzole: what it does to spinal and brainstem neurons and how it does it.
Riluzole exerts central and peripheral modulating effects in amyotrophic lateral sclerosis.
Riluzole for the treatment of acute traumatic spinal cord injury: rationale for and design of the NA…
Pharmacology of riluzole in acute spinal cord injury.
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Clinical Trials
Most Relevant Clinical Trials
Riluzole in Fragile X Syndrome
Riluzole in Mild Alzheimer's Disease
Riluzole Effects on Hippocampus Biomarkers
Riluzole in the Treatment of Bipolar Depression
Riluzole to Treat Major Depression
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