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QuickView for ritonavir (compound)


Genetic Markers

Most Correlated Genes

  1. CYP3A4
  2. FABP1
  3. ALB
  4. CYP4A11
  5. HP
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Pathway Enrichment

Most Correlated Biogroups

  1. response to organic substance
  2. cytosol
  3. response to stress
  4. cellular response to stress
  5. organic cyclic compound binding
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Curated Studies

Most Correlated Studies

  1. Hepatic progenitor HepaRG cells treated with compounds that cause liver injury
  2. Liver tissues from rats after treatment with different compounds
  3. Drug Matrix In Vivo Toxicogenomic Study - Rat Kidney [Affymetrix]
  4. Drug Matrix In Vivo Toxicogenomic Study - Rat Kidney [Codelink]
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Literature

Most Relevant Literature

  1. Population pharmacokinetics of lopinavir/ritonavir in Covid-19 patients.
  2. Comparative effectiveness of Lopinavir/Ritonavir-based regimens in COVID-19.
  3. Drug repositioning of antiretroviral ritonavir for combinatorial therapy in glioblastoma.
  4. In severe COVID-19, adding lopinavir-ritonavir to usual care did not improve mortality at 28 days.
  5. Hybridized nanoamorphous micellar dispersion using a QbD-DM3 linked rational product design strategy…
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Clinical Trials

Most Relevant Clinical Trials

  1. Pharmacokinetics of Low Dose Ritonavir
  2. Titrating-Dose of Lonafarnib in Combination With Ritonavir
  3. Pyronaridine/Artesunate -Ritonavir Drug Drug Interaction Study
  4. Drug-drug Interaction Study Between Lopinavir/Ritonavir and Isavuconazole
  5. Pharmacokinetics of Generic Lopinavir/Ritonavir in Pregnant Women
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