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QuickView for roflumilast (compound)


Genetic Markers

Most Correlated Genes

  1. LCN2
  2. STAC3
  3. NREP
  4. SDHD
  5. A2M
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Pathway Enrichment

Most Correlated Biogroups

  1. response to organic substance
  2. response to stress
  3. regulation of nitrogen compound metabolic process
  4. mitochondrion
  5. cytosol
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Curated Studies

Most Correlated Studies

  1. Livers of rat exposed to variety of hepatotoxic compounds
  2. Drug Matrix In Vivo Toxicogenomic Study - Rat Heart [Codelink]
  3. Drug Matrix In Vivo Toxicogenomic Study - Rat Liver [Affymetrix]
  4. Drug Matrix In Vivo Toxicogenomic Study - Rat Liver [Codelink]
  5. Liver Pharmacology and Xenobiotic Response Repertoire
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Literature

Most Relevant Literature

  1. In chronic plaque psoriasis, roflumilast cream safely increased likelihood of clear or almost clear …
  2. Trial of Roflumilast Cream for Chronic Plaque Psoriasis.
  3. Glucocorticoid Receptor α Mediates Roflumilast's Ability to Restore Dexamethasone Sensitivity in COP…
  4. Roflumilast, a phosphodiesterase-4 inhibitor, improves hyperoxia-induced lung injury via anti-inflam…
  5. Roflumilast, a Phosphodiesterases-4 (PDE4) Inhibitor, Alleviates Sepsis‑induced Acute Kidney Injury.
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Clinical Trials

Most Relevant Clinical Trials

  1. Roflumilast in ARDS
  2. Post Marketing Surveillance of Roflumilast in Korea
  3. Efficacy of Roflumilast in the Treatment of Psoriasis
  4. Long-term Observational Study of the Safety of Roflumilast
  5. Strategy to Improve Adherence of Roflumilast
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