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spinocerebellar ataxia
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NextBio Summary
General Info
Genetic Markers
Most Correlated Genes
Most Correlated SNPs
TDP1
SCAX5
WDR73
CACNA1G
H1F0
No SNPs found
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Pathway Enrichment
Most Correlated Biogroups
CAGTGTT_MIR141_MIR200A
GSE10147_IL3_VS_IL3_AND_HIVP17_STIM_PDC_UP
synapse
AACTTT_UNKNOWN
GGGAGGRR_MAZ_Q6
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Curated Studies
Most Correlated Studies
Friedreich’s ataxia induced pluripotent stem cells
Lymphoblastoid cell lines of Spinocerebellar Ataxia Type 28 patients (mutated AFG3L2)
Cerebella, midbrains and livers from 6mo, 12mo and 24mo old ATXN2 knockout mice
Neural progenitors from Friedreich ataxia patient iPSCs (induced pluripotent stem cells)
Cerebella from SCA6 MPI 118Q/118Q and MPI 11Q/11Q knockin spinocerebellar ataxia mouse models
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Literature
Most Relevant Literature
Rating scales and biomarkers for CAG-repeat spinocerebellar ataxias: Implications for therapy develo…
Spinocerebellar ataxia clinical trials: opportunities and challenges.
Gene Therapy for Polyglutamine Spinocerebellar Ataxias: Advances, Challenges, and Perspectives.
Molecular spectrum, family screening and genetic counselling of Spinocerebellar Ataxia (SCA) cases i…
Diagnostic efficacy of the magnetic resonance T1w/T2w ratio for the middle cerebellar peduncle in mu…
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Clinical Trials
Most Relevant Clinical Trials
Dalfampridine and Gait in Spinocerebellar Ataxias
Identification of Biomarkers in Spinocerebellar Ataxia 3
Study of CAD-1883 for Spinocerebellar Ataxia
Measuring Neurological Impairment and Functional Visual Assessment In Spinocerebellar Ataxias
Efficacy Of Oral Trehalose In Spinocerebellar Ataxia 3
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