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thymidylate synthase
(gene)
Summary
General Info
Body Atlas
Most Correlated Tissues
Granulocyte-macrophage progenitor cell of bone marrow
Hematopoietic stem cell of bone marrow
Thymus gland
Bone marrow
Testes
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Disease Atlas
Most Correlated Diseases
Epstein-Barr virus disease
Anomaly of chromosome pair 12
Disease due to Retroviridae
Disease due to Lentivirus
Bacterial septicemia
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Pharmaco Atlas
Most Correlated Compounds
raltitrexed
Floxuridine
pemetrexed
Leucovorin
5-(6)-carboxyfluorescein diacetate succinimidyl ester
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Knockdown Atlas
Most Correlated Gene Perturbations
PRM7
MIR103A2
SATB1
PDE6B
CASP4
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Curated Studies
Most Correlated Studies
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Literature
Most Relevant Literature
Caught in Action: X-ray Structure of Thymidylate Synthase with Noncovalent Intermediate Analog.
Bacterial versus human thymidylate synthase: Kinetics and functionality.
Concerted versus stepwise mechanism in thymidylate synthase.
The effect of high pressure on the intracellular trehalose synthase activity of Thermus aquaticus.
Mg2+ binds to the surface of thymidylate synthase and affects hydride transfer at the interior activ…
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Clinical Trials
Most Relevant Clinical Trials
Capecitabine as Second-Line Therapy in Treating Patients With Stage IV Pancreatic Cancer Who Have th…
Response Prediction in Metastasized Colorectal Cancer Using Intratumoral Thymidylate Synthase
Pemetrexed/Cisplatin Versus Gemcitabine/Cisplatin According to Thymidylate Synthase Expression
A Phase I Trial of ZD1694 (TOMUDEX), an Inhibitor of Thymidylate Synthase, in Pediatric Patients Wit…
Open-label, Multicenter, Randomized Phase II Trial of Treatment With Cisplatin and Pemetrexed or Cis…
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