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QuickView for topiramate (compound)


Genetic Markers

Most Correlated Genes

  1. GRIK1
  2. GABRA1
  3. SCN1A
  4. CA2
  5. CA4
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Pathway Enrichment

Most Correlated Biogroups

  1. GSE13229_IMM_VS_INTMATURE_NKCELL_UP
  2. MODULE_324
  3. neuron projection
  4. somatodendritic compartment
  5. STAT1_03
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
  2. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
  3. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
  4. Whole blood of methamphetamine dependent patients pre and post topiramate or placebo treatment
  5. Broad Connectivity Map (CMAP 2.0) compound database
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Literature

Most Relevant Literature

  1. Phentermine/topiramate for the treatment of obesity.
  2. Topiramate is likely to act outside of the trigeminocervical complex.
  3. Topiramate maculopathy.
  4. Effects of topiramate on dysaesthetic pain in a patient with multiple sclerosis.
  5. Hypohidrosis induced by topiramate in an adult patient.
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Clinical Trials

Most Relevant Clinical Trials

  1. Topiramate to Reduce Cocaine Dependence
  2. Topiramate Trial for Compulsive Buying
  3. Topiramate for Alcohol and Cocaine Dependence
  4. Topiramate Treatment of Problem Drinkers
  5. The Prolonged Use of Topiramate for Preventing Migraine Headaches
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