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QuickView for transthyretin (gene)


Body Atlas

Most Correlated Tissues

  1. Cerebellar vermis
  2. Liver
  3. Fetal liver
  4. Cerebellum peduncles
  5. Thalamus
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Disease Atlas

Most Correlated Diseases

  1. Amyloidosis
  2. Neuropathy
  3. Bacterial infection due to Bacillus
  4. Non-fatal electric shock
  5. Low blood pressure
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Pharmaco Atlas

Most Correlated Compounds

  1. quintozene
  2. Leukemia Inhibitory Factor
  3. iodoform
  4. norflurane
  5. 2,2-bis(bromomethyl)-1,3-propanediol
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. Mir30a
  2. ARX
  3. RABL6
  4. CDX2
  5. EZH1
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. Plasma transthyretin is a nutritional biomarker in human morbidities.
  2. Destabilisation of the structure of transthyretin is driven by Ca2.
  3. Calcium Binds to Transthyretin with Low Affinity.
  4. High-avidity binding drives nucleation of amyloidogenic transthyretin monomer.
  5. Transthyretin: Its function and amyloid formation.
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Clinical Trials

Most Relevant Clinical Trials

  1. Exercise Effect on Transthyretin Stability
  2. Biomarker for Transthyretin-Related Familial Amyloidotic Polyneuropathy (BioTRAP)
  3. The Effect of Tafamidis on Transthyretin Stabilization, Safety, Tolerability and Efficacy in Transth…
  4. Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Polyneurophathy
  5. Short-term Effects of TOLCAPONE on Transthyretin Stability in Subjects With Leptomeningeal TTR Amylo…
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