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tumor protein p53
(gene)
Summary
General Info
Body Atlas
Most Correlated Tissues
B lymphocyte (IgM memory) of spleen
Granulocyte-macrophage progenitor cell of bone marrow
Nipple cross-section
Tonsil
Endometrium
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Disease Atlas
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Curated Studies
Most Correlated Studies
Breast cancer MDA-MB-231 cells with p53 siRNA treated with TNF-a
Pancreatic cancer in KPC mouse model after CTGF inhibition and gemcitabine treatment
Malignant pleural mesothelioma cells and xenografts - mithramycin treated or overexpressing P53
Neuroblastoma SHEP cells with dox-induced/uninduced MYCN before or after nutlin-3a treatment
MCF7 cell response to individual or combined activation of p53, estrogen receptor, and NFKB
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Literature
Most Relevant Literature
p53: A tale of complexity and context.
Targeting Mutant-p53 for Cancer Treatment: Are We There Yet?
An overview of the functions of p53 and drugs acting either on wild- or mutant-type p53.
TP53 to mediate immune escape in tumor microenvironment: an overview of the research progress.
Water Leakage Pathway Leads to Internal Hydration of the p53 Core Domain.
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Clinical Trials
Most Relevant Clinical Trials
A Pilot Trial of Atorvastatin in Tumor Protein 53 (p53) -Mutant and p53 Wild-Type Malignancies
CT-011 and p53 Genetic Vaccine for Advanced Solid Tumors
p53 Vaccine for Ovarian Cancer
Phase II Study of Metastatic Cancer That Overexpresses P53 Using Lymphodepleting Conditioning Follow…
Chemo-immunotherapy (Gemcitabine, Interferon-alpha 2b and p53 SLP) in Patients With Platinum-resista…
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