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ubiquitin ligase
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Curated Studies
Most Correlated Studies
Prostate cancer PC3 cells with shRNA-silenced RNF2 or RNF2 inhibited by PRT4165 or GW-516
Acute monocytic leukemia MOLM-13 cells treated with the stapled peptide ALRN-6924
Acute monoblastic leukemia MOLM-13 cells treated with potent TRIM24 inhibitors IACS-9571 and dTRIM24
Acute leukemia cells treated with cell-permeable chemical degrader of TRIM24
Colon cancer cells treated with a small molecule inhibitor of HUWE1 and shRNA for HUWE1 or MIZ1
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Literature
Most Relevant Literature
Attenuation of HOIL-1L ligase activity promotes systemic autoimmune disorders by augmenting linear u…
The HOIL-1L ligase modulates immune signalling and cell death via monoubiquitination of LUBAC.
Systematic HOIP interactome profiling reveals critical roles of linear ubiquitination in tissue home…
HOIL-1L deficiency induces cell cycle alteration which causes immaturity of skeletal muscle and card…
Mechanistic insights into the homo-dimerization of HOIL-1L and SHARPIN.
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Clinical Trials
Most Relevant Clinical Trials
The Role of RING Ubiquitin Ligases in Biologic and Oncologic Processes in Tissues of Mesenchymal Ori…
Smurf2 Gene Expression in Urinary Tract Tumors
Angelman Syndrome (AS) Biomarker Study
Effect of BCAA Supplementation on Muscle Mass, Muscle Quality and Molecular Markers of Muscle Regene…
Study on the Brain Network of Angelman Syndrome
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