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17- allylamino- 17- demethoxygeldanamycin
Summary
General Info
Curated Studies
Most Correlated Studies
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
Broad Connectivity Map (CMAP 2.0) compound database
Prostate cancer LnCaP cells treated with bicalutamide, 17-AAG or SAHA
PC3 cells treated with Wee1 inhibitor II and 17AAG
A2780 and MCF7 cancer cell lines treated with CDK, HSP90, and topoisomerase inhibitors
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Literature
Most Relevant Literature
HSP90 inhibitors 17-AAG and VER-82576 inhibit porcine deltacoronavirus replication in vitro.
In vivo antitumor efficacy of 17-AAG loaded PMMA in a human multiple myeloma xenograft mouse model.
The HSP90 inhibitor 17-AAG induced calcium-mediated apoptosis in filarial parasites.
Capsaicin binds the N-terminus of Hsp90, induces lysosomal degradation of Hsp70, and enhances the an…
HSP90 inhibitor 17AAG attenuates sevoflurane-induced neurotoxicity in rats and human neuroglioma cel…
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Clinical Trials
Most Relevant Clinical Trials
PXD101 and 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Metastatic or Unresect…
Imatinib Mesylate and 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Chronic Mye…
17-Dimethylaminoethylamino-17-Demethoxygeldanamycin (17-DMAG) in Treating Patients With Metastatic S…
17-N-Allylamino-17-Demethoxygeldanamycin With or Without Rituximab in Treating Patients With Relapse…
17AAG to Treat Kidney Tumors in Von Hippel-Lindau Disease
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