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5 hydroxytryptamine
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Summary
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Genetic Markers
Most Correlated Genes
SLC35E2
SMAD3
POLH
MMP16
SMG7
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Pathway Enrichment
Most Correlated Biogroups
OSMAN_BLADDER_CANCER_UP
GSE6269_HEALTHY_VS_STAPH_AUREUS_INF_PBMC_UP
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_UP
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Curated Studies
Most Correlated Studies
SK-N-SH neuroblastoma cells treated with risperidone
PBMC of patients with major depression (MD) or subsyndromal symptomatic depression (SSD)
Cortical pyramidal S100a10+ or Glt25d2+ cells treated with fluoxetine
Cortex gene expression of mouse strains treated with Fluoxetine
Expression data from human Jurkat T cells exposed to 31 compounds
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Literature
Most Relevant Literature
Fifty years on: Serotonin and depression.
Linezolid-associated serotonin toxicity: a systematic review.
Serotonin syndrome.
Systematic review of studies using platelet serotonin content to assess bioeffect of serotonin reupt…
Serotonin syndrome-A focused review.
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Clinical Trials
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Randomized Placebo Controlled Trial Evaluating the Efficacy of Pimavanserin, a Selective Serotonin 5…
An Investigation of the Antidepressant Efficacy of the 5-HT2A Antagonist, M100907, in Combination Wi…
Association of 5-HT3 Receptor Gene Polymorphism With the Efficiency of Ondansetron for Postoperative…
Evaluation of [11C]Cimbi-36 as an Agonist PET Radioligand for Imaging of 5-HT2A Receptors
PET Imaging of Brain 5-HT(1A) Receptors Using [(11)C](-)-RWAY
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