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QuickView for 7-dehydrocholesterol reductase activity (biogroup)


Body Atlas

Most Correlated Tissues

  1. Fetal liver
  2. Adrenal gland
  3. Adrenal gland cortex
  4. Adipose tissue
  5. Nipple cross-section
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Disease Atlas

Most Correlated Diseases

  1. Disorder of cholesterol synthesis
  2. Septicemia due to Klebsiella
  3. Eating / feeding / drinking finding
  4. Liver transplant disorder
  5. High fat diet
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Pharmaco Atlas

Most Correlated Compounds

  1. insulin-like growth factor-1, mouse
  2. lupeol
  3. Riluzole
  4. Propanil
  5. N'-(3,4-dihydroxybenzylidene)-3-hydroxy-2-naphthahydrazide
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. OTUD1
  2. LACTB
  3. STK38
  4. DBI
  5. CDH3
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Curated Studies

Most Correlated Studies

  1. Mouse Phenotypes - Multiple malformation syndrome, moderate short stature, facial
  2. OMIM - Congenital disorder
  3. Embryo exposure to heat shock and the teratogen 4-hydroperoxycyclophosphamide
  4. Neuronal stem cells treated with benzimidazole-5-carboxamide derivative X5050
  5. L1000 CMAP Breast cancer MCF7 cells with gene overexpression perturbations
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Literature

Most Relevant Literature

  1. Rapid identification of Smith-Lemli-Opitz syndrome homozygotes and heterozygotes (carriers) by measu…
  2. Regulation of cholesterol biosynthetic pathway in patients with the Smith-Lemli-Opitz syndrome.
  3. Studies on the inhibitory mechanism of some hypocholesterolemic agents on 7-dehydrocholesterol delta…
  4. Markedly inhibited 7-dehydrocholesterol-delta 7-reductase activity in liver microsomes from Smith-Le…
  5. Regulation of the last two enzymatic reactions in cholesterol biosynthesis in rats: effects of BM 15…
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Clinical Trials

Most Relevant Clinical Trials

  1. Simvastatin Therapy in Smith-Lemli-Opitz Syndrome
  2. SLOS: The Effect of Simvastatin in Patients Receiving Cholesterol Supplementation
  3. Study of Smith-Lemli-Opitz Syndrome
  4. Vitamin D Supplementation in the Armed Forces
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