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rs6983267
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ABCG2
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NextBio Summary
General Info
Body Atlas
Most Correlated Tissues
Ileum mucosa
Colon mucosa
Rectum colon
Small intestine
Transverse colon
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Disease Atlas
Most Correlated Diseases
Porphyria
Ulceration of intestine
Gout
Hyperuricemia
Colitis
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Pharmaco Atlas
Most Correlated Compounds
Granulocyte-Macrophage Colony-Stimulating Factor
beta Catenin
Roundup
cyclopamine
ZM 447439
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Knockdown Atlas
Most Correlated Gene Perturbations
KLF1
ABCG2
UXT
USF1
EMP2
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Curated Studies
Most Correlated Studies
Breast carcinoma SUM149 cells with EMP2 shRNA knockdown
Non-small cell lung cancer NCI-H1299 cells with PRKCI or SOX2 shRNA knockdown
Bronchoepithelial cell polysome and total RNA fractions from severe asthma patients
Hepatic progenitor HepaRG cells treated with compounds that cause liver injury
Colonic mucosa adjacent to and away from the tumor of patients with sporadic colorectal cancer
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Literature
Most Relevant Literature
ABCG2 requires a single aromatic amino acid to "clamp" substrates and inhibitors into the binding po…
The ABCG2 Q141K hyperuricemia and gout associated variant illuminates the physiology of human urate …
Abcg2-expressing side population cells contribute to cardiomyocyte renewal through fusion.
Mdr1a, Bcrp and Mrp2 regulate the efficacy and toxicity of mesaconitine and hypaconitine by altering…
Moderate hypoxia modulates ABCG2 to promote the proliferation of mouse spermatogonial stem cells by …
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Clinical Trials
Most Relevant Clinical Trials
Genetic Polymorphisms of ABCG2/BCRP on the Transport of Nifedipine to Breast Milk.
Evaluation of the Relationship Between ABCG2 Mutation and Teriflunomide Exposure and Safety in Chine…
Oxaliplatin - Induced Peripheral Neuropathy in Patients With Gastrointestinal Tract Cancer
Multidrug Resistance Genes in Patients With Acute Myeloid Leukemia
Studying Biomarkers in Samples From Patients With Recurrent or Metastatic Head and Neck Cancer Treat…
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