QuickView for APOBEC2 (gene)

1. Melanoma cell line DNA copy number variations
2. Chromophobe renal cell carcinoma copy number variation analysis
3. Skin from alopecia areata allografts treated with ruxolitinib or tofacitinib
4. Gastric cancer cell lines YCC3, AGS, and KATOIII with KLF5, GATA4, or GATA6 knockdown
5. Retinas from diabetic LEPR[db/db] or lean non-diabetic LEPR[db/+] mice

1. Excessive activity of apolipoprotein B mRNA editing enzyme catalytic polypeptide 2 (APOBEC2) contrib…
2. Apobec2 deficiency causes mitochondrial defects and mitophagy in skeletal muscle.
3. APOBEC2 negatively regulates myoblast differentiation in muscle regeneration.
4. Deficiency in APOBEC2 leads to a shift in muscle fiber type, diminished body mass, and myopathy.
5. Modulating APOBEC expression enhances DNA vaccine immunogenicity.

There were no clinical trials for APOBEC2