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QuickView for Altretamine (compound)


Genetic Markers

Most Correlated Genes

  1. ADCY10
  2. TUBA1A
  3. TOLLIP
  4. HAAO
  5. CYP1A1
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Pathway Enrichment

Most Correlated Biogroups

  1. response to organic substance
  2. regulation of nitrogen compound metabolic process
  3. response to stress
  4. heterocyclic compound binding
  5. enzyme binding
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Curated Studies

Most Correlated Studies

  1. B-cell lymphoma cell lines treated by 92 FDA approved compounds - a timecourse
  2. Livers of rat exposed to variety of hepatotoxic compounds
  3. Drug Matrix In Vivo Toxicogenomic Study - Rat Liver [Affymetrix]
  4. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
  5. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
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Literature

Most Relevant Literature

  1. Hexamethylmelamine as consolidation treatment for patients with advanced epithelial ovarian cancer i…
  2. Liposomes incorporating sodium deoxycholate for hexamethylmelamine (HMM) oral delivery: development,…
  3. Synergy of irofulven in combination with other DNA damaging agents: synergistic interaction with alt…
  4. Atom efficient cyclotrimerization of dimethylcyanamide catalyzed by aluminium amide: a combined expe…
  5. Oral altretamine used as salvage therapy in recurrent ovarian cancer.
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Clinical Trials

Most Relevant Clinical Trials

  1. Altretamine and Etoposide in Treating Patients With HIV-Related Cancer
  2. Prevention of Delayed Nausea A Phase III Double-Blind Placebo-Controlled Clinical Trial
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