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QuickView for Apolipoprotein L1 (gene)


Body Atlas

Most Correlated Tissues

  1. Bladder
  2. Plasma cell of spleen
  3. Atrioventricular node
  4. Macrophage of peripheral blood
  5. Liver
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Disease Atlas

Most Correlated Diseases

  1. Glomerulosclerosis
  2. Enteritis of small intestine
  3. Contact dermatitis
  4. Mycobacteriosis
  5. Zika virus disease
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Pharmaco Atlas

Most Correlated Compounds

  1. Ornithogalum glycoside
  2. Antibodies
  3. CP 690,550
  4. IFN-alpha21a(1-95), IFN-alpha2c(96-165) fusion protein
  5. ustekinumab
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. UCA1
  2. FBXO11
  3. NFKBIA
  4. ADAR
  5. CHMP2A
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. Apolipoprotein L1 and mechanisms of kidney disease susceptibility.
  2. Molecular Dynamic Simulation Reveals Structure Differences in APOL1 Variants and Implication in Path…
  3. A glomerular transcriptomic landscape of apolipoprotein L1 in Black patients with focal segmental gl…
  4. Stakeholder Perspectives on Returning Nonactionable Apolipoprotein L1 (APOL1) Genetic Results to Afr…
  5. The evolving story of apolipoprotein L1 nephropathy: the end of the beginning.
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Clinical Trials

Most Relevant Clinical Trials

  1. APOL1 Genetic Testing Program for Living Donors
  2. APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO)
  3. Phase 2a Study of VX-147 in Adults With APOL1-mediated Focal Segmental Glomerulosclerosis
  4. APOL1 Genetic Testing in African Americans
  5. Phase 2/3 Adaptive Study of VX-147 in Adults and Adolescents With APOL1- Mediated Proteinuric Kidney…
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