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QuickView for Arsenic trioxide (compound)


Genetic Markers

Most Correlated Genes

  1. PML
  2. SLC7A11
  3. MT1E
  4. HSP26
  5. HSPA6
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Pathway Enrichment

Most Correlated Biogroups

  1. ribosome biogenesis
  2. ribonucleoprotein complex biogenesis
  3. preribosome
  4. nucleolus
  5. cellular nitrogen compound biosynthetic process
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Curated Studies

Most Correlated Studies

  1. Cultured human lung epithelial cells gene expression following chronic arsenic exposure
  2. Expression data from human Jurkat T cells exposed to 31 compounds
  3. Drug target sets for approved compounds
  4. Arsenite stress response in Saccharomyces cerevisiae
  5. Multiple myeloma cell lines treated with arsenic and darinaparsin
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Literature

Most Relevant Literature

  1. Arsenic trioxide: an ancient drug revived.
  2. Inhibition of AKT enhances mitotic cell apoptosis induced by arsenic trioxide.
  3. Retinoic acid and arsenic trioxide for acute promyelocytic leukemia.
  4. Impact of arsenic trioxide in the treatment of acute promyelocytic leukemia.
  5. Hepatotoxicity from arsenic trioxide for pediatric acute promyelocytic leukemia.
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Clinical Trials

Most Relevant Clinical Trials

  1. Arsenic Trioxide for Structural p53 Mutations
  2. Arsenic Trioxide in Treating Patients With Myelodysplastic Syndromes
  3. Arsenic Trioxide in Treating Patients With Relapsed or Refractory Lymphoma or Leukemia
  4. The Effect of Arsenic Trioxide on Eliminating HIV-1 Reservoir Combined With cART
  5. Treatment of Chronic Graft Versus Host Disease With Arsenic Trioxide
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