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BCR ABL
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General Info
Curated Studies
Most Correlated Studies
BCR-ABL positive Adult Acute Lymphoblastic Leukemia
Gleevec treatment of BCR-ABL positive and negative leukemia cell lines
LSK bone marrow cells tranformed with combinations of BCR-ABL and NUP98-HOXA9
Effects of BCR-ABL expression in long-term repopulating hematopoietic stem cells
Spleens of mice transplanted with stem cells expressing fusion proteins BCR/ABL and ABL/BCR
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Literature
Most Relevant Literature
Three atypical BCR/ABL transcripts detected simultaneously in a Philadelphia-positive acute lymphobl…
Cell-Active, Reversible, and Irreversible Covalent Inhibitors That Selectively Target the Catalytic …
Single amino acid-based PROTACs trigger degradation of the oncogenic kinase BCR-ABL in chronic myelo…
De nove Philadelphia chromosome-positive myelodysplastic syndromes with complex karyotype and p230 B…
Myristoyl's dual role in allosterically regulating and localizing Abl kinase.
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Clinical Trials
Most Relevant Clinical Trials
Study to Evaluate Tolerability, Safety, Pharmacokinetics and Preliminary Efficacy of PF-114 for Oral…
Phase II Front-line Ponatinib in Adult Philadelphia+/BCR-ABL+ Acute Lymphoblastic Leukemia.
Pharmacokinetic Profile of Vincristine Administered With Imatinib for Bcr-Abl Positive Acute Lymphob…
Front-line Nilotinib Treatment of BCR-ABL+ Chronic Myeloid Leukaemia in Chronic Phase
Philadelphia Chromosome Positive CML Patients Without Optimal Response or Tolerance to Bcr-Abl TKI
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