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Bumetanide
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Summary
General Info
Genetic Markers
Most Correlated Genes
SLC12A1
ATP1A1
NOLC1
IFI6
NPM3
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Pathway Enrichment
Most Correlated Biogroups
THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP
HALLMARK_PROTEIN_SECRETION
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP
SENESE_HDAC1_TARGETS_UP
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Curated Studies
Most Correlated Studies
Expression data from human Jurkat T cells exposed to 31 compounds
Cerebrocortical cells treated with blood-brain barrier penetrant clinic-tested drugs
Liver tissues from rats after treatment with different compounds
Genomics Assisted Toxicity Evaluation system study - Human Hepatocytes
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
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Literature
Most Relevant Literature
Bumetanide reduces seizure frequency in patients with temporal lobe epilepsy.
Bumetanide prevents transient decreases in muscle force in murine hypokalemic periodic paralysis.
GPR35 is a target of the loop diuretic drugs bumetanide and furosemide.
cAMP-stimulated Cl- secretion is increased by glucocorticoids and inhibited by bumetanide in semicir…
Clinical pharmacology of the loop diuretics furosemide and bumetanide in neonates and infants.
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Clinical Trials
Most Relevant Clinical Trials
Bumetanide in Hypokalaemic Periodic Paralysis
Bumetanide Versus Furosemide in Heart Failure
Evaluation of the Efficacy and Safety of Bumetanide in Parkinson's Disease
Pilot Study of Bumetanide for Newborn Seizures
Efficiency of Bumetanide in Autistic Children
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