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C5aR
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Body Atlas
Most Correlated Tissues
Leukocyte (polymorphonuclear) of peripheral blood
Neutrophil of bone marrow
Microglial cell
Mononuclear cell of peripheral blood
Monocyte of peripheral blood
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Literature
Most Relevant Literature
Mechanism of activation and biased signaling in complement receptor C5aR1.
Modulation of C5a-C5aR1 signaling alters the dynamics of AD progression.
The anaphylatoxin C5a: Structure, function, signaling, physiology, disease, and therapeutics.
The C5a/C5aR1 Axis Contributes to the Pathogenesis of Acute Cystitis Through Enhancement of Adhesion…
Inhibition of C5AR1 impairs osteoclast mobilization and prevents bone loss.
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Clinical Trials
Most Relevant Clinical Trials
IPH5401 (Anti-C5aR) in Combination With Durvalumab in Patients With Advanced Solid Tumors
Dose-escalation Trial of Anti-C5aR Antibody in Healthy Subjects
Avdoralimab an Anti-C5aR Antibody, in Patients With COVID-19 Severe Pneumonia ( FORCE )
Complement C5a Receptors in Hidradenitis Suppurativa
C5a Receptor Expression - COVID-19 (C5-COV)
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