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CDK 9
Summary
General Info
Curated Studies
Most Correlated Studies
B cell lymphoma VAL and OCI-LY3 cells treated with CDK-9 inhibitor AZ5576 compound
Peripheral blood mononuclear, DU145, and HCT116 cells treated with R547 CDK inhibitor
Yeast cell cycle transcription dynamics in a Cdk1-deficient strain
T cell acute lymphoblastic leukemia MOLT4 cells treated with cyclin-dependent kinase inhibitors
Embryonic gene expression in 3-fold staged daf-19 and daf-12 mutants
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Literature
Most Relevant Literature
CDK9 inhibitors for the treatment of solid tumors.
Transcriptional regulation and therapeutic potential of cyclin-dependent kinase 9 (CDK9) in sarcoma.
Potent inhibitors targeting cyclin-dependent kinase 9 discovered via virtual high-throughput screeni…
Selective inhibition of CDK9 in triple negative breast cancer.
Identification of a Novel Selective CDK9 Inhibitor for the Treatment of CRC: Design, Synthesis, and …
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Clinical Trials
Most Relevant Clinical Trials
Palbociclib After CDK and Endocrine Therapy (PACE)
A First-in-Human Study of CDK-002 (exoSTING) in Subjects With Advanced/Metastatic, Recurrent, Inject…
A Phase 1/2a Study of CDK-003 in Patients With Cutaneous T-Cell Lymphoma (CTCL).
CDK 4/6 Inhibitor, Ribociclib, With Adjuvant Endocrine Therapy for ER-positive Breast Cancer
A Study of exoASO-STAT6 (CDK-004) in Patients With Advanced Hepatocellular Carcinoma (HCC) and Patie…
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