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CDK4 protein
Summary
General Info
Curated Studies
Most Correlated Studies
Transplanted HCmel3 mouse melanomas relapsing post adoptive T-cell (ACT) therapy
HeLa cells after G0-G1 / G1-S arrest release with CDK4/6 shRNA and IL-1a treated
Mantle cell lymphoma in Cdk4R24C c-myc-3’RR transgenic mice
Mantle cell lymphomas from c-MYC-transgenic mice with CDK4[R24C] or TP53 mutations
Cyclin D1 and CDK4 contribute to the undifferentiated phenotype in neuroblastoma
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Literature
Most Relevant Literature
miR-122-5p Mediates Fluoride-Induced Osteoblast Activation by Targeting CDK4.
MicroRNA-338-3p Inhibits Proliferation and Promotes Apoptosis of Multiple Myeloma Cells Through Targ…
Development of Selective Cyclin-Dependent Kinase 4 Inhibitors for Antineoplastic Therapies.
Cyclin-dependent kinase 4-related tubular epithelial cell proliferation is regulated by Paired box g…
Impact of cyclin-dependent kinase CDK4 inhibition on eryptosis.
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Clinical Trials
Most Relevant Clinical Trials
Study of the CDK4/6 Inhibitor Abemaciclib in Solid Tumors Harboring Genetic Alterations in Genes Enc…
Lenvatinib+Letrozole Versus Fulvestrant in Metastatic ER+/HER2- Breast Cancer, Post Progression on A…
Targeted Therapy With CDK4/6 Inhibitors in Chemo-Refractory, Rb Wild-Type Extensive SCLC
Study to Assess the Efficacy and Safety of Alpelisib Plus Fulvestrant in Participants With HR-postit…
Liquid-biopsy Informed Platform Trial to Evaluate CDK4/6-inhibitor Resistant ER+/HER2- Metastatic Br…
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