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QuickView for CYP2D6 (gene)


Body Atlas

Most Correlated Tissues

  1. Liver
  2. Skeletal muscle psoas
  3. Transverse colon
  4. Atrioventricular node
  5. Superior cervical ganglion
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Disease Atlas

Most Correlated Diseases

  1. Propensity to adverse reactions to drug
  2. Parkinson's disease
  3. Sendai virus infection
  4. Disorder of basal ganglia
  5. Movement disorder
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Pharmaco Atlas

Most Correlated Compounds

  1. Niridazole
  2. Lisuride
  3. Midodrine
  4. sulfabenzamide
  5. Anabasine
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. MYT1L
  2. PARK7
  3. NR2E1
  4. POU3F2
  5. GHR
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. PharmVar GeneFocus: CYP2D6.
  2. Prescribed Doses of CYP2D6-Metabolized Drugs and Hemodynamic Responses in Relation to CYP2D6 Genotyp…
  3. Human CYP2D6 Is Functional in Brain In Vivo: Evidence from Humanized CYP2D6 Transgenic Mice.
  4. Influence of CYP2D6*5 and *10 polymorphism on the pharmacokinetics of nebivolol in healthy Chinese s…
  5. Inhibitory effects of polyphenols and their colonic metabolites on CYP2D6 enzyme using two different…
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Clinical Trials

Most Relevant Clinical Trials

  1. Effects of Isotretinoin on CYP2D6 Activity
  2. Evaluation of Pupillometry for cyp2d6 Phenotyping in Children Treated With Tramadol
  3. CYP2D6 Pharmacogenetics in Risperidone-Treated Children
  4. Biomarkers of CYP2D6 and CYP3A4 Variability in Pediatrics
  5. Effects of Retinoids on CYP2D6 Activity During Pregnancy
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