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DHODH
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Body Atlas
Most Correlated Tissues
Liver
Plasma cell of spleen
Granulocyte-macrophage progenitor cell of bone marrow
B lymphocyte (IgM memory) of spleen
Rectum colon
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Disease Atlas
Most Correlated Diseases
Hepatocellular dysplasia
Acute hepatic failure
Hepatic failure
Liver cancer
Liver transplant disorder
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Pharmaco Atlas
Most Correlated Compounds
minaprine
Halcinonide
lactofen
Pivampicillin
Pneumovax
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Knockdown Atlas
Most Correlated Gene Perturbations
SUC2
C15orf65
NCL
CIITA
AMY1A
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Curated Studies
Most Correlated Studies
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Literature
Most Relevant Literature
A novel mitochondria-targeting DHODH inhibitor induces robust ferroptosis and alleviates immune supp…
Proline and dihydroorotate dehydrogenase promote a hyper-proliferative state and dampen ferroptosis …
Kinetic and structural studies of Mycobacterium tuberculosis dihydroorotate dehydrogenase reveal new…
The Warburg effect modulates DHODH role in ferroptosis: a review.
Identification of second generation benzylidene chromanone analogues as novel, potent DHODH inhibito…
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Clinical Trials
Most Relevant Clinical Trials
Study to Evaluate the Efficacy and Safety of Oral RP7214, a DHODH Inhibitor, in Patients With Sympto…
A Single and Multiple Ascending and Food Effect Study of RP7214, a DHODH Inhibitor in Healthy Adult …
A Study to Investigate BAY2402234, a Dihydroorotate Dehydrogenase (DHODH) Inhibitor, in Myeloid Mali…
Targeting de Novo Pyrimidine Biosynthesis by Leflunomide for the Treatment of COVID-19 Virus Disease
Phase 2 Dose-finding IMU-838 for Ulcerative Colitis
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