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Disulfiram
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
CA3
GK
MT2A
AKR1B15
EREG
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Pathway Enrichment
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response to organic substance
FISCHER_DREAM_TARGETS
PUJANA_BRCA1_PCC_NETWORK
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP
LEE_BMP2_TARGETS_DN
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Curated Studies
Most Correlated Studies
Glioma pediatric high grade SF188 and GPC16 cells treated with disulfiram
Genomics Assisted Toxicity Evaluation system study - Human Hepatocytes
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
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Literature
Most Relevant Literature
Bi-layered disulfiram-loaded fiber membranes with antibacterial properties for wound dressing.
Disulfiram relieves severe acute pancreatitis by inhibiting GSDMD-dependent NETs formation.
Effects and Mode of Action of Oleic Acid and Tween 80 on Skin Permeation of Disulfiram.
Leveraging disulfiram to treat cancer: Mechanisms of action, delivery strategies, and treatment regi…
Clinical, pharmacological, and formulation evaluation of disulfiram in the treatment of glioblastoma…
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Clinical Trials
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DISulfiram for COvid-19 (DISCO) Trial
Disulfiram in Recurrent Glioblastoma
Pharmacogenetics of Disulfiram for Cocaine
Open-Label Disulfiram for Methamphetamine Dependence
Disulfiram for Treatment of Retinal Degeneration
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