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Dot1l
(gene)
Summary
General Info
Body Atlas
Most Correlated Tissues
Testes
Bone marrow
Kidney cortex
Thymus gland
Pituitary gland
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Disease Atlas
Most Correlated Diseases
Pyloric ulcer
Infection due to Mycobacterium tuberculosis
Brucellosis
Traumatic injury
Tularemia
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Most Correlated Compounds
marimastat
trinitrophenyl-bovine serum albumin
Puromycin
2,4-diaminoquinazoline
Cobalt
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Most Correlated Gene Perturbations
DOT1
ZSCAN5A
MYOC
APEH
LEP
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Most Correlated Studies
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Literature
Most Relevant Literature
Dot1l cooperates with Npm1 to repress endogenous retrovirus MERVL in embryonic stem cells.
DOT1L promotes spermatid differentiation by regulating expression of genes required for histone-to-p…
DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres.
The histone methyltransferase DOT1L is a new epigenetic regulator of pulmonary fibrosis.
DOT1L regulates lipid biosynthesis and inflammatory responses in macrophages and promotes atheroscle…
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Clinical Trials
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A Phase 1 Dose Escalation and Expanded Cohort Study of EPZ-5676 in the Treatment of Pediatric Patien…
A Phase 1, Open-Label, Dose-Escalation & Expanded Cohort, Continuous IV Infusion, Multi-center Study…
Testing Olaparib in Patients With Advanced or Metastatic (Cancer That Has Spread) Bladder Cancer and…
Pinometostat and Azacitidine in Treating Patients With Relapsed, Refractory, or Newly Diagnosed Acut…
Pinometostat With Standard Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leuk…
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