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ENPP1
(gene)
Summary
General Info
Body Atlas
Most Correlated Tissues
Liver
Thyroid gland
Myometrium
Joint synovium
Transverse colon
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Disease Atlas
Most Correlated Diseases
Idiopathic arterial calcification of infancy
Low blood pressure
Hypertrophy of bone
Arthropathy
Disorder of glucose metabolism
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Pharmaco Atlas
Most Correlated Compounds
Amifostine
ascaris suum 14-kDa antigen
Probiotic mixture
anacardic acid
CAL 101
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Knockdown Atlas
Most Correlated Gene Perturbations
VPS26A
SNRNP40
TNFRSF11A
IFRD2
NRF1
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Curated Studies
Most Correlated Studies
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Literature
Most Relevant Literature
Structure-Aided Development of Small-Molecule Inhibitors of ENPP1, the Extracellular Phosphodiestera…
ENPP1 Immunobiology as a Therapeutic Target.
Discovery of VH domains that allosterically inhibit ENPP1.
ENPP1 is an innate immune checkpoint of the anticancer cGAMP-STING pathway.
NPP1 and TNAP hydrolyze ATP synergistically during biomineralization.
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Clinical Trials
Most Relevant Clinical Trials
Understanding the Spectrum of ENPP1 Deficiency and Acute ABCC6 Deficiency
The ENERGY Study: Evaluation of Safety and Tolerability of INZ-701 in Infants With ENPP1 Deficiency
Evaluation of Safety, Tolerability, and Efficacy of INZ-701 in Adults With ENPP1 Deficiency
Natural History Study of ENPP1 Deficiency and and the Early-onset Form of ABCC6 Deficiency
Natural History of GACI With or Without ARHR2 or PXE
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