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Estrone
(compound)
Summary
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Genetic Markers
Most Correlated Genes
ESR1
EGR3
DNAJB9
NCKAP1L
ATM
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Pathway Enrichment
Most Correlated Biogroups
MASSARWEH_TAMOXIFEN_RESISTANCE_DN
BHAT_ESR1_TARGETS_NOT_VIA_AKT1_DN
BHAT_ESR1_TARGETS_VIA_AKT1_DN
HALLMARK_ESTROGEN_RESPONSE_EARLY
DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN
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Curated Studies
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Drug target sets for approved compounds
Broad Connectivity Map (CMAP 2.0) compound database
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
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Literature
Most Relevant Literature
Endometrial and endometriotic concentrations of estrone and estradiol are determined by local metabo…
Comparison of estrone and 17β-estradiol levels in commercial goat and cow milk.
17β-Estradiol, but not estrone, increases the survival and activation of new neurons in the hippocam…
Long-term prospective study of the influence of estrone levels on events in postmenopausal women wit…
Synthesis and cytotoxic activities of estrone and estradiol cis-dichloroplatinum(II) complexes.
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Clinical Trials
Most Relevant Clinical Trials
Superovulation And Urinary Concentration of Estrone
Comparison of Perilipin, Leptin, Adipolipin, Adiponectin, Resistin, Visfatin, Estrone Levels Pre-pos…
Phase 2a Obesity Study of Oral Doses of Oleoyl-Estrone (MP-101)
Phase 2a Randomized, Double-Blind Study of Oleoyl-Estrone in Male Morbidly Obese Adults
A Trial to Assess the Pharmacokinetic Profile (e.g., Uptake, Distribution and Excretion of a Substan…
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